Voltammetric behavior of vitamin B2 on the gold electrode modified with a self-assembled monolayer of l-cysteine and its application for the determination of vitamin B2 using linear sweep stripping voltammetry

The voltammetric behavior of Vitamin B2 (VB2) has been studied at the gold electrode modified with a self-assembled monolayer of l-cysteine. The voltammetric responses are evaluated with respect experimental conditions, such as composition and pH of the supporting electrolyte, concentration of VB2, accumulation potential and accumulation time. On basis of the voltammetric behavior a highly sensitive method is present for the determination of VB2 by using linear sweep stripping volammetry. The method is suitable for the determination of VB2 concentrations between 5.0×10−11 and 5.0×10−6 mol l−1. And the detection limit can be reached to 2.5×10−11 mol l−1. The method is applied to determine the concentration of VB2 in the tablets with satisfactory results.