Title of article
Efficient synthesis of purine analogues: an FeCl3–SiO2-promoted cyclization reaction of 4,5-diaminopyrimidines with aldehydes leading to 6,8,9-trisubstituted purines
Author/Authors
Dang، نويسنده , , Qun and Brown، نويسنده , , Brian S and Erion، نويسنده , , Mark D، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
6559
To page
6562
Abstract
6,8,9-Trisubstituted purine analogues were efficiently synthesized via cyclization of 6-chloro-4,5-diaminopyrimidines and various aldehydes promoted by FeCl3–SiO2. Fe(III) chloride on silica gel has a dual role of a dehydration agent and an oxidant, and was conveniently removed during work-up by filtration.
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1642824
Link To Document