Title of article
Synthesis of picropodophyllin homolactone
Author/Authors
Roulland، نويسنده , , Emmanuel and Bertounesque *، نويسنده , , Emmanuel and Huel، نويسنده , , Christiane and Monneret، نويسنده , , Claude، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
5
From page
6769
To page
6773
Abstract
Based on a Wittig olefination strategy, the first synthesis of picropodophyllin homolactone 2 is described in nine steps and 30% overall yield from podophyllotoxine 1. The relative configuration of 2 was unambiguously determined using 2D NOESY NMR and a Monte Carlo search protocol. This work corrects the literature on the synthesis of 2.
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1642932
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