Title of article
Li+ and Na+ switch of enantioselectivity in the desymmetrisation of polycyclic bis(phenylsulfonyl)alkenes by chiral alcohols
Author/Authors
Cossu، نويسنده , , Sergio and De Lucchi *، نويسنده , , Ottorino and Peluso، نويسنده , , Paola and Volpicelli، نويسنده , , Raffaella، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
7263
To page
7266
Abstract
A complete switch of enantioselectivity is obtained in the desymmetrisation reaction of polycyclic bis(phenylsulfonyl)alkenes by the change of the base from n-BuLi to NaH, thus allowing convenient access to either enantiomer of polycyclic ketones with the same chiral auxiliary.
Keywords
enantiotopic discrimination , desymmetrisation , polycyclic ketones , Sulfones
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1643164
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