Author/Authors :
Li، نويسنده , , Yulin and Liu، نويسنده , , Zuosheng and Lan، نويسنده , , Jiong and Li، نويسنده , , Jing Tian Peng، نويسنده , , Lizeng and Li، نويسنده , , Weidong Z and Li، نويسنده , , Ying and Chan، نويسنده , , Albert S.C، نويسنده ,
Abstract :
The first enantioselective total synthesis of (+)-11,12-epoxycembrene-C (1), a novel naturally occurring cembranoxide isolated from tropical marine soft coral, was achieved via a general approach by employing an intramolecular McMurry coupling and Sharpless asymmetric epoxidation as key steps from readily available starting materials.
Keywords :
cembrane diterpenoid , Sharpless epoxidation , 12-epoxycembrene-C , total synthesis , McMurry coupling , 11
