Title of article
Pd-catalyzed hydrogenolysis of 4,5-epoxy-2-alkenoates: model study of the acyl side-chain of polyoxypeptin
Author/Authors
Noguchi، نويسنده , , Yasuo and Yamada، نويسنده , , Tatsuhiro and Uchiro، نويسنده , , Hiromi and Kobayashi، نويسنده , , Susumu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
5
From page
7493
To page
7497
Abstract
Palladium-catalyzed hydrogenolysis of 4,5-epoxy-2-alkenoates to 5-hydroxy-2-alkenoates was examined, and it was shown that the (Z)-alkenoate with a bulky substituent at C-4 underwent hydrogenolysis with a decrease in the stereospecificity. Mechanistic considerations and steps for improvement of the stereospecificity are also presented.
Keywords
Pd-catalyzed hydrogenolysis , 4 , ?–?–? interconversion , 5-epoxy-2-alkenoate , polyoxypeptin
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1643222
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