Title of article
Parallel synthesis of 1,2,4-oxadiazoles from carboxylic acids using an improved, uronium-based, activation
Author/Authors
Poulain، نويسنده , , Rébecca F and Tartar، نويسنده , , André L and Déprez، نويسنده , , Beno??t P، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
1495
To page
1498
Abstract
We describe the synthesis of 1,2,4-oxadiazoles from carboxylic acids and amidoximes using 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU) as an activating agent of the carboxylic acid function for the O-acylation step. This method was used for the synthesis of a library of 24 1,2,4-oxadiazoles.
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1643247
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