Author/Authors :
Heath، نويسنده , , Perry C and Huang، نويسنده , , Charles Q and Lowe، نويسنده , , Richard F and McCarthy، نويسنده , , James R and Weigel، نويسنده , , Leland O and Whitten، نويسنده , , Jeffery P، نويسنده ,
Abstract :
Acylation of 1,3-disubstituted thioureas with methyl malonyl chloride followed by base-catalyzed cyclization leads to the preparation of 1,3-disubstituted-2-thiobarbituric acids in high yield.
