Pd-catalyzed acylation of α,β-ynone with acylzirconocene chloride and one-pot formation of cyclopentenone derivatives

Acylzirconocene chloride as an ‘unmasked’ acyl anion donor reacted with α,β-ynones to give 1,4-regioselective acylation products by the use of a catalytic amount of PdCl2(PPh3)2 or Pd(PPh3)4, and a formation of a cyclopentenone derivative is observed through the reaction of α,β-unsaturated acylzirconocene chlorides and α,β-unsaturated ynones.