• Title of article

    Regioselective alkylation of guanines using 2-acetoxytetrahydrofurans

  • Author/Authors

    Geen، نويسنده , , Graham R and Kincey، نويسنده , , Peter M and Spoors، نويسنده , , P.Grant، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    4
  • From page
    1781
  • To page
    1784
  • Abstract
    Reaction of silylated guanine derivatives with 2-acetoxy-4-benzoyloxymethyltetrahydrofuran in DMF or NMP resulted in selective N-9 alkylation. This was used as the basis for a regioselective synthesis of the anti-viral agents famciclovir and penciclovir.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1643481

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1643481