Title of article :
A general and versatile synthesis of 2-alkyl-4-aminopyridines
Author/Authors :
Hegde، نويسنده , , Vidyadhar B and Renga، نويسنده , , James S. and Owen، نويسنده , , John M، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
A versatile two-step synthesis of 2-alkyl-4-aminopyridines from commercially available cis-1-methoxy-1-buten-3-yne is described. Acylation of the yne derivative followed by amination and cyclization in ammonia produced the desired substituted pyridines in high yield.
Keywords :
Aminopyridines , cis-1-methoxy-1-butyn-3-yne , acetylenic ketones
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters