Title of article
New NADH models bearing a phosphonate or a chiral oxazaphospholidine oxide at the dihydropyridine ring
Author/Authors
Vasse، نويسنده , , Jean-Luc and Goumain، نويسنده , , Sophie and Levacher، نويسنده , , Vincent and Dupas، نويسنده , , Georges and Quéguiner، نويسنده , , Guy and Bourguignon، نويسنده , , Jean، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
1871
To page
1873
Abstract
Novel NADH models bearing a phosphonate at the 3-position of a stable 1,4-dihydroquinoline structure were successfully involved in the reduction of methyl benzoylformate. Asymmetric reduction of the former ketone with a NADH model bearing a chiral oxazaphospholidine oxide is reported affording methyl benzoylformate in 45% e.e.
Keywords
coenzyme models , non chiral or chiral phosphonic acid derivatives , biomimetic reduction
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1643557
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