Author/Authors :
Alezra، نويسنده , , Valérie and Bonin، نويسنده , , Martine and Micouin، نويسنده , , Laurent and Husson، نويسنده , , Henri-Philippe Husson، نويسنده ,
Abstract :
A new route towards the asymmetric preparation of quaternary 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives has been developed. The key step involves an intramolecular Pictet–Spengler reaction of an oxazolidino ester.
