Title of article :
Synthesis of methyl 3-amino-2-hydroxy-4-phenylbutanoates, important core intermediates for peptide mimics possessing biological activities
Author/Authors :
Nemoto، نويسنده , , Hisao and Ma، نويسنده , , Rujian and Li، نويسنده , , Xinming and Suzuki، نويسنده , , Ichiro and Shibuya، نويسنده , , Masayuki، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
Core intermediates for the synthesis of anti-cancer agents, inhibitors of aminopeptidases and HIV proteases, 3-amino-2-hydroxy-4-phenylbutanoates were synthesized by using H-C(CN)2O-SiR3 as a key reagent.
Keywords :
amino acids and derivatives , amino aldehydes , acyl cyanides , acyl anion equivalents , Biologically active compounds
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
