Title of article
Synthesis of methyl 3-amino-2-hydroxy-4-phenylbutanoates, important core intermediates for peptide mimics possessing biological activities
Author/Authors
Nemoto، نويسنده , , Hisao and Ma، نويسنده , , Rujian and Li، نويسنده , , Xinming and Suzuki، نويسنده , , Ichiro and Shibuya، نويسنده , , Masayuki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
2145
To page
2147
Abstract
Core intermediates for the synthesis of anti-cancer agents, inhibitors of aminopeptidases and HIV proteases, 3-amino-2-hydroxy-4-phenylbutanoates were synthesized by using H-C(CN)2O-SiR3 as a key reagent.
Keywords
amino acids and derivatives , amino aldehydes , acyl cyanides , acyl anion equivalents , Biologically active compounds
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1643773
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