Efficient synthesis of unsymmetrically disubstituted ferrocenes: towards electrochemical dipeptide-Fc-biosensors

Unsymmetrically disubstituted ferrocenes (1a, 1b), electrochemical dipeptide-Fc-biosensors, were synthesized by a straightforward synthetic method from 1,1′-ferrocenedicarboxylic acid. In addition, an efficient solution synthesis of pentapeptide (2) was reported.