Title of article :
A facile synthesis of 2,5-diketopiperazines based on isocyanide chemistry
Author/Authors :
Stefano Marcaccini، نويسنده , , Stefano and Pepino، نويسنده , , Roberto and Pozo، نويسنده , , Ma? Cruz، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
The Ugi four-component condensation (4-CC) between amines 4, aromatic aldehydes 5, chloroacetic acid 6 and isocyanides 7 afforded the expected 4-CC adducts 8 which were cyclised to the title compounds 9 upon treatment with ethanolic KOH under ultrasonication.
Keywords :
piperazine/piperazinones , Sonochemistry , Isocyanides , Ugi–Passerini reactions
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters