Title of article
Functionalized eight-membered lactams via [3,3] sigmatropic rearrangement of 2-azetidinone-tethered 1,5-dienes
Author/Authors
Alcaide، نويسنده , , Benito and Rodr??guez-Ranera، نويسنده , , Carolina and Rodr??guez-Vicente، نويسنده , , Alberto، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
3081
To page
3083
Abstract
The thermally induced [3,3] sigmatropic (Cope) rearrangement of cis-β-lactams 1 having alkenyl groups at both the C3 and C4 positions to yield new functionalized eight-membered lactams (tetrahydroazocinones) 2, in racemic as well as optically pure forms, is reported. This process involves a novel, concerted C3C4 bond breakage of the β-lactam nucleus helped by ring strain.
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1644493
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