• Title of article

    Functionalized eight-membered lactams via [3,3] sigmatropic rearrangement of 2-azetidinone-tethered 1,5-dienes

  • Author/Authors

    Alcaide، نويسنده , , Benito and Rodr??guez-Ranera، نويسنده , , Carolina and Rodr??guez-Vicente، نويسنده , , Alberto، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    3
  • From page
    3081
  • To page
    3083
  • Abstract
    The thermally induced [3,3] sigmatropic (Cope) rearrangement of cis-β-lactams 1 having alkenyl groups at both the C3 and C4 positions to yield new functionalized eight-membered lactams (tetrahydroazocinones) 2, in racemic as well as optically pure forms, is reported. This process involves a novel, concerted C3C4 bond breakage of the β-lactam nucleus helped by ring strain.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1644493