Title of article
Tandem glycol cleavage—intramolecular 4+2 cycloadditions mediated by Mn(OAc)3
Author/Authors
Maria and Ignacio Candela Lena، نويسنده , , José Ignacio and Rico Ferreira، نويسنده , , Maria del Rosario and Mart??n Hernando، نويسنده , , José Ignacio and Alt?nel، نويسنده , , Ertan and Arseniyadis، نويسنده , , Siméon، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
3179
To page
3182
Abstract
The Mn(OAc)3 mediated oxidative cleavage of 1 and 2 proceeded as expected, while molecular diversity was generated upon cleavage of their unsaturated counterparts 5 and 6 via a tandem glycol cleavage/4+2 process. Minor products of the reaction were identified as the α-dicarbonyl derivative (i.e. 25) and the corresponding cross-conjugated hydroxy dienone (i.e. 26). The process tolerates a variety of substitution patterns and protecting groups. A brief comparison with the Pb(OAc)4 initiated cascade transformations is presented.
Keywords
glycol cleavage , Tandem reactions , manganic acetate , lead tetraacetate , bis-hetero IMDA
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1644565
Link To Document