Title of article :
α-Aminocyclopropanone hydrates: potential transition-state analog inhibitors of serine proteases
Author/Authors :
Doris ، نويسنده , , Eric and Wagner، نويسنده , , Alain and Mioskowski، نويسنده , , Charles، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
The synthesis of two α-aminocyclopropanone hydrates is reported. These synthons could find biological applications by acting as transition-state analog inhibitors of hydrolytic enzymes, such as serine proteases.
Keywords :
Cyclopropanation , Enzyme inhibitors , cyclopropanones
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
