• Title of article

    Direct synthesis of α-substituted phosphonates

  • Author/Authors

    Praveen Kumar، نويسنده , , K and Muthiah، نويسنده , , C and Kumaraswamy، نويسنده , , Sudha and Kumara Swamy، نويسنده , , K.C، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    3
  • From page
    3219
  • To page
    3221
  • Abstract
    The α-substituted phosphonates (OCH2CMe2CH2O)P(O)CH(X)(Ar) [X=Cl, OMe, NMe2 and OSiMe3], useful precursors for Horner–Wadsworth–Emmons reactions, are readily prepared by treating (OCH2CMe2CH2O)PX with an aromatic aldehyde. In the reaction of (OCH2CMe2CH2O)PCl with furfuraldehyde and cinnamaldehyde, the 5-chlorofurfurylphosphonate (OCH2CMe2CH2O)P(O)CH2(5-Cl-C4H2O) and the γ-chlorophosphonate (OCH2CMe2CH2O)P(O)CHCH-CH(Cl)Ph, respectively, are formed in good yields.
  • Keywords
    Phosphonates , Abramov reaction
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1644595

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1644595