Title of article
A macrolactonization-based strategy to obtain microtuble-stabilizing agent (−)-laulimalide
Author/Authors
Ghosh، نويسنده , , Arun K and Wang، نويسنده , , Yong، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
3399
To page
3401
Abstract
An alternative synthesis of anti-tumor macrolide (−)-laulimalide is described. The synthesis was achieved utilizing Yamaguchi macrolactonization as the key step. The sensitive C2–C3 cis-olefin functionality has been installed by a macrolactonization of hydroxy alkynic acid and subsequent hydrogenation over Lindlarʹs catalyst.
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1644722
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