Title of article :
A novel linker for the solid-phase synthesis of a library of 3′-thiophosphorylated dinucleotides
Author/Authors :
Roland، نويسنده , , Arlène and Xiao، نويسنده , , Yufang and Jin، نويسنده , , Yi and Iyer، نويسنده , , Radhakrishnan P، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
The preparation of a controlled-pore-glass (CPG) support carrying a novel linker is described. This support was compatible with the established phosphoramidite method of solid-phase oligonucleotide synthesis. The use of this linker for the synthesis of a library of 3′-thiophosphorylated dinucleotides is described.
Keywords :
solid-support , 3?-thiophosphorylation , automated synthesis , Combinatorial chemistry , dinucleotides
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
