Title of article
Solid-phase synthesis of functionalized tropane derivatives via 1,3-dipolar cycloaddition
Author/Authors
Caix-Haumesser، نويسنده , , Sandrine and Hanna، نويسنده , , Issam and Lallemand، نويسنده , , Jean-Yves and Peyronel، نويسنده , , Jean-François، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
3721
To page
3723
Abstract
1,3-Dipolar cycloaddition of 3-oxidopyridinium betaine to activated olefins on solid-phase leads to resin-bound 8-azabicyclo[3.2.1]octenones which undergo further transformations such as 1,4-addition of nucleophiles. Cleavage of benzyl linker is achieved using acid chlorides in the presence of potassium iodide to give substituted tropane derivatives.
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1644968
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