Author/Authors :
Luo، نويسنده , , Yue and Evindar، نويسنده , , Ghotas and Fishlock، نويسنده , , Dan and Lajoie، نويسنده , , Gilles A، نويسنده ,
Abstract :
Two efficient and convenient syntheses of N-Cbz and N-Fmoc N-methyl serine and threonine are described. The amino acid side-chain alcohol can be protected as a TBDMS ether in very good yield or left free, followed by the formation and subsequent reduction of the corresponding oxazolidinone.