Title of article
Expeditious preparation of 2-substituted quinolines
Author/Authors
Fakhfakh، نويسنده , , Mohamed A and Franck، نويسنده , , Xavier and Fournet، نويسنده , , Alain and Hocquemiller، نويسنده , , Reynald and Figadère، نويسنده , , Bruno، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
3847
To page
3850
Abstract
A library of 2-substituted quinolines was synthesized in solution from mixtures of Grignard reagents and a quinolinium salt. Grignard reagents were prepared in one pot, taking advantage of the entrainment method for their preparation from unreactive alkyl halides. Then mixtures of 2-alkylquinolines were readily accessible for biological tests or separated by centrifugal-partition chromatography (CPC) prior to the biological screening.
Keywords
multi-components reaction , Quinolines , Grignard reagents
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1645074
Link To Document