Reaction of Baylis–Hillman products with Swern and Dess–Martin oxidants
Author/Authors :
Lawrence، نويسنده , , Nicholas J and Crump، نويسنده , , J.Paul and McGown، نويسنده , , Alan T. and Hadfield، نويسنده , , John A، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Pages :
3
From page :
3939
To page :
3941
Abstract :
The Baylis–Hillman adducts of aryl aldehydes and alkyl acrylates are efficiently oxidized to the corresponding α-methylene-β-keto esters with the Dess–Martin periodinane. The attempted Swern oxidation of the same adducts resulted in SN2′-type substitution of the allylic hydroxyl group by chloride.
