Title of article
A short and efficient synthesis of enantiopure (+)-N-Boc-7-azabicyclo[2.2.1]heptan-2-one utilizing an asymmetric desymmetrization protocol: formal total synthesis of (−)-epibatidine
Author/Authors
Pandey، نويسنده , , Ganesh and Tiwari، نويسنده , , Shashi Kant and Singh، نويسنده , , Ram Shanker and Mali، نويسنده , , Raghao S، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
3947
To page
3949
Abstract
A short and efficient synthesis of optically pure (+)-N-Boc-azabicyclo[2.2.1]hept-2-one (2), a precursor in the synthesis of natural (−)-epibatidine (1), is reported by the asymmetric desymmetrization of meso-N-methoxycarbonyl-2,3-bis(phenylsulfonyl)-7-azabicyclo[2.2.1]hept-2-ene (3).
Keywords
asymmetric desymmetrization , Epibatidine
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1645149
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