Lowering the detection limit of calcium selective ISFETs with polymeric membranes

Detection limits of Ca sensitive ISFETs with photocured polyurethane membranes with a neutral carrier and an ion-exchanger as ionophores are studied. It is shown that conditioning of ISFETs in solutions containing only interfering ions results in reduction of the detection limit. Zero-current ion fluxes approach elaborated for polymeric membrane ion-selective electrodes (ISEs) is used to explain the obtained results.