Title of article :
Efficient total synthesis of 5-oxo-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid (5-oxo-ETE), a potent proinflammatory autacoid
Author/Authors :
Mohapatra، نويسنده , , Suchismita and Capdevila، نويسنده , , Jorge H and Murphy، نويسنده , , Robert C and Hevko، نويسنده , , John M and Falck، نويسنده , , J.R، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
The title eicosanoid was prepared in good overall yield via a convergent aldol strategy that obviates the need for HPLC separation of olefinic isomers.
Keywords :
Eicosanoids , aldol reactions , Biologically active compounds , Hydrogenation , metabolites
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters