Title of article
Enantioselective Michael addition catalyzed by chiral tripodal oxazoline–tBuOK complexes
Author/Authors
Kim، نويسنده , , Sung-Gon and Han Ahn، نويسنده , , Kyo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
4175
To page
4177
Abstract
Benzene-based tripodal oxazolines are found to be novel chiral ligands for the catalytic enantioselective Michael addition via potassium enolates. Thus, methyl phenylacetate undergoes 1,4-addition to methyl acrylate using a catalytic amount of a tBuOK–oxazoline complex in toluene at −78°C, and up to 82% ee is obtained.
Keywords
asymmetric catalyst , tripodal oxazoline , Michael addition , potassium enolate
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1645338
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