Stereoselective syntheses of aminocyclopentitols: a norbornyl approach

Synthesis of some novel aminocyclopentitol analogues has been achieved through a functionally embellished cyclopentanoid derivative of well-defined stereochemical disposition, obtained via a Grob-type fragmentation sequence executed within the norbornyl framework. The glycosidase inhibition studies of the new aminocyclopentitols indicate them to be weak inhibitors.