Advanced precursors in marine biosynthetic study. Part 2: The biosynthesis of isocyanides and isothiocyanates in the tropical marine sponge Axinyssa n.sp.

The biosynthetic origins of the isocyanide and isothiocyanate groups in 9-isocyanopupukeanane (2) and 9-isothiocyanatopupukeanane (3) are investigated by incorporation of [14C]-labelled advanced precursors into the sponge Axinyssa n.sp.