Title of article :
Towards the synthesis of C-glycosylated dihydropyrimidine libraries via the three-component Biginelli reaction. A novel approach to artificial nucleosides
Author/Authors :
Dondoni، نويسنده , , Alessandro and Massi، نويسنده , , Alessandro and Sabbatini، نويسنده , , Simona، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
The Lewis acid catalyzed (BF3·Et2O, CuCl, AcOH) one-pot three-component cyclocondensation of urea with C-glycosylated aldehydes and β-keto esters (Biginelli reaction) in a combinatorial manner afforded three different series of 3,4-dihydropyrimidin-2(1H)-ones bearing C-glycosyl moieties at C4, C6, and at both C4 and C6.
Keywords :
Dihydropyrimidines , Biginelli reaction , multicomponent reaction , C-Glycosides
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
