Author/Authors :
Brandsma، نويسنده , , Lambert and Spek، نويسنده , , Anthony L and Trofimov، نويسنده , , Boris A and Tarasova، نويسنده , , Olʹga A and Nedolya، نويسنده , , Nina A and Afonin، نويسنده , , Andrei V and Zinshenko، نويسنده , , Sergei V، نويسنده ,
Abstract :
Reaction of dilithiated benzylacetylene PhCH(Li)-CC-Li with one equivalent of an isothiocyanate RNCS followed by successive addition of t-BuOH, a solution of t-BuOK in DMSO and methyl iodide gives exclusively a cyclobutene or a thietane derivative if R=t-Bu or Ph, respectively, and mixtures of the expected thiophene, the cyclobutene and thietane derivatives if R=Me.
Keywords :
Dilithiation , Rearrangement , cyclization , cyclobutenes , thietanes