Title of article
Solid-phase synthesis of 3-hydroxymethyl isoxazoles via resin bound nitrile oxides
Author/Authors
Cereda، نويسنده , , Enzo and Ezhaya، نويسنده , , Antoine and Quai، نويسنده , , Monica and Barbaglia، نويسنده , , Walter، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
4951
To page
4953
Abstract
[3+2] Cycloaddition of alkynes to resin bound nitrile oxides gives after cleavage of 3,4,5 trisubstituted isoxazoles in acceptable yields and fair to good purity, depending on the alkyne substituents. The reaction has been automated on the ACT 496 synthesiser.
Keywords
solid-phase synthesis , Combinatorial chemistry , Isoxazoles
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1645927
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