Title of article :
An expedient route to aromatic pyrrolo[2,1-c][1,4]benzodiazepines and a study of their reactivity
Author/Authors :
Fabis، نويسنده , , Frédéric and Sopkova-de Oliveira Santos، نويسنده , , Jana and Fouchet-Jolivet، نويسنده , , Sandrine and Rault، نويسنده , , Sylvain، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
2-Hydroxypyrrolo[2,1-c][1,4]benzodiazepines were aromatised in refluxing thionyl chloride into 11-chloropyrrolo[2,1-c][1,4]benzodiazepines in high yield. This aromatic system is doubly reactive towards nucleophiles leading to rearranged products such as iminobenzoxazines and quinazolines.
Keywords :
Thionyl chloride , iminobenzoxazine , quinazoline , 4]benzodiazepine , Aromatisation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
