Title of article :
Zamamistatin, a significant antibacterial bromotyrosine derivative, from the Okinawan sponge Pseudoceratina purpurea
Author/Authors :
Takada، نويسنده , , Noboru and Watanabe، نويسنده , , Reiko and Suenaga، نويسنده , , Kiyotake and Yamada، نويسنده , , Kaoru and Ueda، نويسنده , , Katsuhiro and Kita، نويسنده , , Masaki and Uemura، نويسنده , , Daisuke، نويسنده ,
Abstract :
Zamamistatin was isolated from the Okinawan sponge Pseudoceratina purpurea. It was determined to be a novel bromotyrosine derivative by careful analysis of 2D NMR spectra and comparison of its 1H NMR spectrum with those of structurally related compounds. The absolute stereostructure of zamamistatin was determined by the modified Mosherʹs method. Zamamistatin exhibited significant antibacterial activity against Rhodospirillum salexigens, which has adhering properties.
Keywords :
antifouling agent , Antibacterial activity , Structural determination , Absolute stereochemistry , Isolation
