New access to α-substituted (Z)-fluoroalkene dipeptide isosteres utilizing organocopper reagents under ‘reduction–oxidative alkylation (R–OA)’ conditions
Author/Authors :
Otaka، نويسنده , , Akira and Watanabe، نويسنده , , Hideaki and Yukimasa، نويسنده , , Akira and Oishi، نويسنده , , Shinya and Tamamura، نويسنده , , Hirokazu and Fujii، نويسنده , , Nobutaka، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Pages :
4
From page :
5443
To page :
5446
Abstract :
(Z)-Fluoroalkene dipeptide isosteres serve as potential dipeptide mimetics. The present paper reports a new access to α-substituted (Z)-fluoroalkene isosteres utilizing an organocopper-mediated ‘reduction–oxidative alkylation (R–OA)’ reaction.