Title of article :
A regiospecific three-component one-step cyclocondensation to 6-cyano-5,8-dihydropyrido[2,3-d]pyrimidin-4(3H)-ones. Using microwaves under solvent-free conditions
Author/Authors :
Quiroga، نويسنده , , Jairo and Cisneros، نويسنده , , Carlos and Insuasty، نويسنده , , Braulio and Abon??a، نويسنده , , Rodrigo and Nogueras، نويسنده , , Manuel and S?nchez، نويسنده , , Adolfo، نويسنده ,
Abstract :
In a solvent-free system, regiospecific three-component one-step cyclocondensation to dihydropyrido[2,3-d]pyrimidin-4(3H)-ones 4 starting from readily available aminopyrimidin-4(3H)-ones 1, benzoylacetonitrile 2 and benzaldehydes 3 by microwave radiation was carried out. This rapid method produces pure products in high yields (70–75%).
