Synthesis of new 1,1-dimethyl-1,2,3,4-tetrahydrophenanthrene derivatives

Four new 1,1-dimethyl-1,2,3,4-tetrahydrophenanthrene derivatives, 1-amino-2-(1-hydroxy-2-propyl)-8,8-dimethyl-5,6,7,8-tetrahydrophenanthrene-3,4-dione 2, 3-amino-2-(1-hydroxy-2-propyl)-8,8-dimethyl-5,6,7,8-tetrahydrophenanthrene-1,4-dione 3, 1,4,9,9-tetramethyl-4,5,9,10,11,12-hexahydro-1H-6-oxa-1,3-diaza-dicyclopenta[a,c]phenanthrene 4, 2,4,9,9-tetramethyl-4,5,9,10,11,12-hexahydro-1,6-dioxa-3-aza-dicyclopenta[a,c]phenanthrene 5, were synthesized by reactions of cryptotanshinone 1, a bioactive component from Salvia miltiorrhiza Bunge, with amino compounds.