Title of article
Reformatsky-type aldol reactions of 4-bromo-4,4-difluoroacetoacetate with aldehydes and ketones
Author/Authors
Wang، نويسنده , , Yanli and Zhu، نويسنده , , Shizheng، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
5741
To page
5744
Abstract
In the presence of zinc and a catalytic amount of copper(I) chloride, 4-bromo-4,4-difluoroacetoacetate 4 reacted with a series of aromatic aldehydes and aryl alkyl ketones to give the corresponding δ-hydroxyl-γ,γ-difluoro-β-ketoesters 6 in good to excellent yields under mild conditions.
Keywords
Zinc , gem-difluoromethylen , Reformatsky reaction , ketones , Aldehydes
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1646527
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