Author/Authors :
Steinreiber، نويسنده , , Andreas and Stadler، نويسنده , , Alexander and Mayer، نويسنده , , Sandra F and Faber، نويسنده , , Kurt and Kappe، نويسنده , , C.Oliver، نويسنده ,
Abstract :
An enantioconvergent synthesis of the aggregation pheromones (R)- and (S)-sulcatol (6-methyl-5-hepten-2-ol) is described. Key steps in the deracemization strategy are sequential combinations of enzymatic resolutions and Mitsunobu inversions. Racemization-free Mitsunobu transformations have been carried out within 5 min by microwave irradiation, providing the desired sulcatyl acetates with clean inversion of chirality.
