Title of article :
Solid-phase synthesis of 1-substituted 4,5-dihydro-1,2,4-triazin-6-ones
Author/Authors :
Blanca Martinez-Teipel، نويسنده , , Blanca and Michelotti، نويسنده , , Enrique and Kelly، نويسنده , , Martha J and Weaver، نويسنده , , Damian G and Acholla، نويسنده , , Francis and Beshah، نويسنده , , Kebede and Teixid?، نويسنده , , Jordi، نويسنده ,
Abstract :
The solid-phase synthesis of 1-substituted 4,5-dihydro-1,2,4-triazin-6-ones from imidate esters and substituted hydrazines is reported. The synthesis starts with the reaction of imidic esters with polymer-bound glycine to form the imidate esters. A rehearsal library of 59 compounds was synthesized.
