Title of article :
Synthesis of 2,6-bis(4R-trialkylsiloxymethyloxazolinyl)pyridines and their use in catalytic asymmetric 1,3-dipolar cycloaddition reactions of nitrones and activated alkenes
Author/Authors :
Iwasa، نويسنده , , Seiji and Tsushima، نويسنده , , Shinji and Shimada، نويسنده , , Tomoo and Nishiyama، نويسنده , , Hisao، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
1,3-Dipolar cycloaddition reaction of aromatic nitrones with 3-alkenoyl-2-oxazolidinones in the presence of chiral 2,6-bis(4R-trialkylsiloxymethyloxazolinyl)pyridine/Ni(II) system proceeds smoothly with high enantioselectivity in up to 99% ee.
Keywords :
nitrone , 1 , pybox , 3-dipolar cycloaddition , Oxazolidinone , nickel , Lewis acid , asymmetric catalyst
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
