Title of article
A new method for the preparation of 1,3-dilithiopropyne: an efficient synthesis of homopropargyl alcohols
Author/Authors
Cabezas، نويسنده , , Jorge A and Pereira، نويسنده , , Albلn R and Amey، نويسنده , , Adam، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
6819
To page
6822
Abstract
Controlled dilithiation of propargyl bromide with two equivalents of n-butyllithium, in the presence of TMEDA, produces the operational equivalent of the dianion 1,3-dilithiopropyne. The latter reacts efficiently with aldehydes and ketones to produce homopropargyl alcohols in a single step route and in high yields.
Keywords
homopropargyl alcohols , homopropargylation , 1 , 3-dilithiopropyne
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1647286
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