Author/Authors :
Zhou، نويسنده , , Ping and Li، نويسنده , , Yanfang and Meagher، نويسنده , , Kristin L and Mewshaw، نويسنده , , Richard G and Harrison، نويسنده , , Boyd L، نويسنده ,
Abstract :
A new efficient method for the preparation of 3-(4-pyridinyl)methylindoles has been developed. The new method involves coupling of indoles with 4-pyridinecarboxaldehyde to give 3-indolyl 4-pyridinyl methanols, which upon treatment with triethylsilane in the presence of trifluoroacetic acid afford 3-(4-pyridinyl)methylindoles in 64–76% overall yield.
