Title of article
A one-step β-selective glycosylation of N-acetyl glucosamine and recombinant chitooligosaccharides
Author/Authors
Boris Vauzeilles، نويسنده , , Boris and Dausse، نويسنده , , Bruno and Palmier، نويسنده , , Sara and Beau، نويسنده , , Jean-Marie، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
7567
To page
7570
Abstract
N-Acetyl glucosamine and chitooligosaccharides are selectively converted into β-glycosides without protection of the other hydroxyl groups by alkylation of the anomeric alkoxides in N,N-dimethylformamide containing lithium bromide. Addition of the lithium salt notably improves the stereoselectivity of the glycosylation of the monomer and the efficiency of the process with higher oligomers.
Keywords
carbohydrates , Glycosidation , Alkylation , Salt effects
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1647890
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