Author/Authors :
Hirasawa، نويسنده , , Hideaki and Taniguchi، نويسنده , , Takahiko and Ogasawara، نويسنده , , Kunio، نويسنده ,
Abstract :
The intramolecular ene reaction of the 1,6-diene on a bicyclo[3.2.1]octane framework proceeds in a highly diastereoselective manner to form a trisubstituted pyrrolidine on the pyran ring in excellent yield. Its stereochemistry has been determined unambiguously by converting it into the known compound serving as a key intermediate of (−)-kainic acid.
