Title of article :
A concise synthesis of l-4,4-difluoroglutamine
Author/Authors :
Meffre، نويسنده , , Patrick and Dave، نويسنده , , Rajesh H and Leroy، نويسنده , , Jacques and Badet، نويسنده , , Bernard، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
l-4,4-Difluoroglutamine 1 of high optical purity was prepared from (R)-Garnerʹs aldehyde 2 using Reformatsky reaction as the key step for introducing the fluorinated side-chain.
Keywords :
Reformatsky reaction , Barton–McCombie deoxygenation , Fluorinated amino acids , Garnerיs aldehyde , Glutamine
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
