Author/Authors :
Kadokura، نويسنده , , Michinori and Wada، نويسنده , , Takeshi and Seio، نويسنده , , Kohji and Moriguchi، نويسنده , , Tomohisa and Huber، نويسنده , , Jochen and Lührmann، نويسنده , , Reinhard and Sekine، نويسنده , , Mitsuo، نويسنده ,
Abstract :
A 5′-terminal 2,2,7-trimethylguanosine-capped trinucleotide block (m32,2,7G5′pppAmpUmpA) was successfully synthesized on a highly cross-linked polystyrene resin by a new method for introduction of the first nucleoside onto the resin and a newly developed pyrophosphorylating agent having a benzotriazolyloxy substitutent as the leaving group.
Keywords :
U1 snRNA , solid-phase synthesis of RNA , TMG-cap , BDCP